Primary burning mouth syndrome (BMS) is a chronic neuropathic intraoral pain condition.
. Primary BMS is most frequent in postmenopausal women, with general population prevalence around 1%.
. Treatment of primary BMS is diﬃcult; best evidence exists for eﬃcacy of topical and systemic clonazepam.
. With advanced diagnostic methods, primary BMS can be classiﬁed into a purely peripheral or central type
or a combination of both types.
. These types seem to diﬀer regarding pathophysiological mechanisms, eﬃcacy of available treatments, and
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