Clinical Trials & Studies

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May 23, 2021

INVITATION TO PARTICIPATE IN BURNING MOUTH SYNDROME RESEARCH STUDY AT KING'S COLLEGE IN LONDON, ENGLAND - Recruitment Dates: May 2021 - December 31, 2021.

We are a team of doctors and researchers from the Orofacial Pain team at King’s College London. We are very interested in the health and needs of the patient with burning mouth syndrome (BMS), and we are conducting a research study called ‘Multimodal Investigation of Peripheral and Central Nervous System Pain Mechanisms in Burning Mouth Syndrome (BMS) using magnetic resonance imaging and psychometry’. The study will be conducted in King’s College Dental Hospital, Denmark Hill, London SE5 9RS.

The neuroimaging study aims at improving our understanding of the underlying mechanisms of the ongoing burning pain that you are having. The study investigates the neural network and changes in response to local or topical analgesic and assesses the psychological impact of BMS on patients. We hope to use the information from this research will allow us to further understand and help developing treatment approaches for patients with BMS to achieve pain relief, reduce systemic drug side effects, and improve patients’ quality of life.

The neuroimaging (MRI scan) burning mouth syndrome studies involve 2 main local interventions, which are clonazepam mouth rinse (MRIBMS) and dental local anaesthetic injections (CPMNP).  It will be conducted in King's College Hospital, Denmark Hill, London. We are recruiting participants now till 31st December 2021.  

In total, participants will be attending 2 sessions for the clonazepam rinse study (MRIBMS) and 3 sessions for combined both clonazepam rinse and dental local anaesthetic injections (CPMNP).   Participants must have pain across the tongue (bilaterally) to participate in the dental local anaesthetic (CPMNP) study. 

 

Visits:  

Session 1: clinical screening and examination 

Session 2: MRI scanning session with & without clonazepam mouth rinse (MRIBMS) 

Session 3: MRI scanning session with & without dental local anaesthetic injection (CPMNP) - recruitment limited to participants with BMS on the tongue, bilaterally. 

 

We are reaching out to invite you to take part in our research. Your participation is crucial to us. Please do not hesitate to contact us at huann.tan@kcl.ac.uk or call +44 07307991125 for further information on the study if you are interested and will like to participate in this study. 

Huann Tan, Ph.D. Student

Faculty of Dentistry, Oral & Craniofacial Sciences, King’s College London

Oral Surgery Department, 4th Floor

King’s College Dental Institute London

Denmark Hill Campus, Bassemer Road

London SE5 9RS

huann.tan@kcl.ac.uk

On behalf of Prof Tara Renton (Lead Orofacial Pain Services at King’s College Dental Institute, London) research team.